Alenura®
Alenura® is a combination product of the glycosaminoglycan heparin and alkalinized lidocaine, that provides immediate pain relief to patients experiencing acute painful episodes of IC/BPS.
Alenura® is supplied as a prefilled syringe for intravesicular administration to the bladder for on demand relief of acute pain episodes.
How It Works
Alkalinized Lidocaine:
- Penetrates the transitional epithelial cell layer
- Provides immediate pain relief
- Helps reduce inflammation
Heparin Sodium:
- Augments the natural GAG layer
- Prevents further infiltration of toxic urine components
- Offers anti-inflammatory & anti-microbial properties
- Helps stabilizes alkalinized lidocaine in Alenura formulation
Alenura® Advantage
- In phase 2 trials, Alenura® consistently demonstrates significant separation from placebo in symptoms of pain relief. Pain relief with Alenura® exceeds that of its individual components alone, and has excellent safety and tolerability
- Alenura® is destined to be the first approved product for treatment of acute pain in IC/BPS, a unique solution to a condition suffered by millions.
- Alenura® is recognized as an effective treatment for IC/BPS. Based on published data using the Alenura® formulation, both the American and European Urology associations recommend the use of lidocaine and heparin instillations as first line drug therapy.
VNX001-104 Clinical Trial
% Change in pain over time
VNX001-105 Clinical Trial
% Change in pain over time
